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URL of this page: /genetics/understanding/dtcgenetictesting/dtctesttypes/

What kinds of direct-to-consumer genetic tests are available?

With direct-to-consumer genetic testing companies offering a variety of tests, it can be challenging to determine which tests will be most informative and helpful to you. When considering testing, think about what you hope to get out of the test. Some direct-to-consumer genetic tests are very specific (such as paternity tests), while other services provide a broad range of health, ancestry, and lifestyle information.

Major types of direct-to-consumer genetic tests include:

Disease risk and health

The results of these tests estimate your genetic risk of developing several common diseases that are caused by environmental factors and multiple variants in several genes. These common diseases include such as celiac disease, Parkinson's disease, and Alzheimer's disease. Some companies also include a person’s carrier status for less common conditions, including cystic fibrosis and sickle cell disease. A carrier is someone who has a gene variant in one copy of the gene that, when present in both copies of the gene, causes a genetic disorder. The tests may also look for certain genetic variations that could be related to other health-related traits, such as weight and metabolism (how a person’s body converts the nutrients from food into energy). These tests may also provide information about how a person may respond to certain drugs (pharmacogenomics).?

Ancestry or genealogy

The results of these tests provide clues about where a person's ancestors might have come from, their ethnicity, and genetic connections between families. For more information, see What is genetic ancestry testing?

Kinship

The results of these tests can indicate whether tested individuals are biologically related to one another. For example, kinship testing can establish whether one person is the biological father of another (paternity testing).?

Lifestyle

The results of these tests claim to provide information about lifestyle factors, such as nutrition, fitness, weight loss, skincare, sleep, and even your wine preferences, based on variations in your DNA. Many of the companies that offer this kind of testing also sell services, products, or programs that they customize on the basis of your test results.

Before choosing a direct-to-consumer genetic test, find out what kinds of health, ancestry, or other information will be reported to you. Most direct-to-consumer genetic tests do not sequence whole genes, but look at only a subset of variants within the genes associated with the conditions or traits they report on. For more comprehensive genetic testing, see a genetics professional. Think about whether there is any information you ?would rather not know. In some cases, you can decline to find out specific information if you tell the company before it delivers your results.?

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